Tomatine Displays Antitumor Potential in In Vitro Models of Metastatic Melanoma

Tomatine Displays Antitumor Potential in In Vitro Models of Metastatic Melanoma

There is a growing interest in the cytotoxic effects of bioactive glycoalkaloids, such as α-tomatine on tumor cells. Here, for the first time, we determine the antitumor potential of tomatine, a mixture of α-tomatine and dehydrotomatine, in metastatic melanoma (MM) cell lines harboring different BRA...

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Bibliographic Details
Main Authors: Simona Serratì, Letizia Porcelli, Stefania Guida, Anna Ferretta, Rosa Maria Iacobazzi, Tiziana Cocco, Immacolata Maida, Gabriella Tamasi, Claudio Rossi, Michele Manganelli, Stefania Tommasi, Amalia Azzariti, Gabriella Guida
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:International Journal of Molecular Sciences
Subjects:
metastatic melanoma
tomatine
angiogenesis
apoptosis
autophagy
Online Access:https://www.mdpi.com/1422-0067/21/15/5243

Internet

https://www.mdpi.com/1422-0067/21/15/5243

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