LTβR overexpression promotes plasma cell accumulation

Multiple myeloma (MM), a malignancy of plasma cells (PCs), has diverse genetic underpinnings and in rare cases these include amplification of the lymphotoxin b receptor (Ltbr) locus. LTβR has well defined roles in supporting lymphoid tissue development and function through actions in stromal and mye...

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Bibliographic Details
Main Authors: Jessica A. Kotov, Ying Xu, Nicholas D. Carey, Jason G. Cyster
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9352096/?tool=EBI