462 Dysfunctional leukocyte mitochondrial metabolism is associated with immune paralysis in critically ill septic patients
OBJECTIVES/GOALS: The host immune response during sepsis is now recognized to have anti-inflammatory pathophysiology. We aim to determine whether mitochondrial dysfunction of leukocytes predicts which critically ill septic patients develop immune paralysis and to identify differences in cellular met...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Cambridge University Press
2022-04-01
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Series: | Journal of Clinical and Translational Science |
Online Access: | https://www.cambridge.org/core/product/identifier/S2059866122002710/type/journal_article |