HRPK-1, a conserved KH-domain protein, modulates microRNA activity during Caenorhabditis elegans development.

microRNAs (miRNAs) are potent regulators of gene expression that function in diverse developmental and physiological processes. Argonaute proteins loaded with miRNAs form the miRNA Induced Silencing Complexes (miRISCs) that repress gene expression at the post-transcriptional level. miRISCs target ge...

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Bibliographic Details
Main Authors: Li Li, Isana Veksler-Lublinsky, Anna Zinovyeva
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-10-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1008067