αvβ3 integrin-specific exosomes engineered with cyclopeptide for targeted delivery of triptolide against malignant melanoma

αvβ3 integrin-specific exosomes engineered with cyclopeptide for targeted delivery of triptolide against malignant melanoma

Abstract Background Melanoma is the most malignant skin tumor and is difficult to cure with the alternative treatments of chemotherapy, biotherapy, and immunotherapy. Our previous study showed that triptolide (TP) exhibited powerful tumoricidal activity against melanoma. However, the clinical potent...

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Bibliographic Details
Main Authors: Yongwei Gu, Yue Du, Liangdi Jiang, Xiaomeng Tang, Aixue Li, Yunan Zhao, Yitian Lang, Xiaoyan Liu, Jiyong Liu
Format: Article
Language:English
Published: BMC 2022-08-01
Series:Journal of Nanobiotechnology
Subjects:
Exosomes
Targeted delivery
cRGD
Triptolide
Malignant melanoma
Online Access:https://doi.org/10.1186/s12951-022-01597-1

Internet

https://doi.org/10.1186/s12951-022-01597-1

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