Data-Driven Analysis of Fluorination of Ligands of Aminergic G Protein Coupled Receptors

Currently, G protein-coupled receptors are the targets with the highest number of drugs in many therapeutic areas. Fluorination has become a common strategy in designing highly active biological compounds, as evidenced by the steadily increasing number of newly approved fluorine-containing drugs. He...

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Bibliographic Details
Main Authors: Wojciech Pietruś, Rafał Kurczab, Dagmar Stumpfe, Andrzej J. Bojarski, Jürgen Bajorath
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/11/11/1647