Apoptosis-inducing factor regulates skeletal muscle progenitor cell number and muscle phenotype.

Apoptosis Inducing Factor (AIF) is a highly conserved, ubiquitous flavoprotein localized in the mitochondrial intermembrane space. In vivo, AIF provides protection against neuronal and cardiomyocyte apoptosis induced by oxidative stress. Conversely in vitro, AIF has been demonstrated to have a pro-a...

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Bibliographic Details
Main Authors: Anne-Sophie Armand, Iman Laziz, Dounia Djeghloul, Sylvie Lécolle, Anne T Bertrand, Olivier Biondi, Leon J De Windt, Christophe Chanoine
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22076146/?tool=EBI