THOC3 interacts with YBX1 to promote lung squamous cell carcinoma progression through PFKFB4 mRNA modification

Abstract The THO complex (THOC) is ubiquitously involved in RNA modification and various THOC proteins have been reported to regulate tumor development. However, the role of THOC3 in lung cancer remains unknown. In this study, we identified that THOC3 was highly expressed in lung squamous cell carci...

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Bibliographic Details
Main Authors: Tao Yu, Qi Zhang, Shao-Kun Yu, Feng-Qi Nie, Mei-Ling Zhang, Qian Wang, Kai-Hua Lu
Format: Article
Language:English
Published: Nature Publishing Group 2023-07-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-023-06008-3