Coinhibitory T-Cell Signaling in Islet Allograft Rejection and Tolerance
Autoaggressive T cells directed against insulin secreting pancreatic β-cells mediate the development of type 1 diabetes. Islet transplantation offers superior glycemic control over exogenous insulin, but chronic immunosuppression limits its broad application. Pathogenic T cells are also important in...
| Những tác giả chính: | , , , , |
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| Định dạng: | Bài viết |
| Ngôn ngữ: | English |
| Được phát hành: |
SAGE Publishing
2006-02-01
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| Loạt: | Cell Transplantation |
| Truy cập trực tuyến: | https://doi.org/10.3727/000000006783982160 |