Novel sulphonamide-azaheterocycle conjugates and their anti-cancer, anti-inflammatory, anti-diabetic, anti-angiogenesis activity and molecular docking studies

The present study reports the synthesis of sulphonamide-azaheterocycle conjugates (3 a-j) and evaluates its in vitro anticancer activity against breast cancer cell line (MCF-7) and liver cancer cell line (HepG2). The compound 3g was found to be the most active compound with IC50 values of 40.54 ± 0....

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों: Pradnya Patil, Nisha Nerlekar, Sanket Rathod, Pradeep Mhaldar, Taha Najm, Prakash Bansode, Jagannath Jadhav, Padma Dandge, Prafulla Choudhari, Dattaprasad Pore, Gajanan Rashinkar
स्वरूप: लेख
भाषा:English
प्रकाशित: Elsevier 2024-01-01
श्रृंखला:Results in Chemistry
विषय:
ऑनलाइन पहुंच:http://www.sciencedirect.com/science/article/pii/S2211715624001723