Food phytochemicals, epigallocatechin gallate and myricetin, covalently bind to the active site of the coronavirus main protease in vitro

Food phytochemicals, epigallocatechin gallate and myricetin, covalently bind to the active site of the coronavirus main protease in vitro

SARS-CoV-2 main protease is a possible target for protection against viral infection. This study examined the inhibitory effect of food phytochemicals on the main protease of SARS-CoV-2 by determining a cleaved product after chromatographic separation. First, 37 phytochemicals, including glycosides...

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Bibliographic Details
Main Authors: Yoji Kato, Akari Higashiyama, Emi Takaoka, Miyu Nishikawa, Shinichi Ikushiro
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:Advances in Redox Research
Subjects:
Coronavirus main protease
Food phytochemical
EGCG
Myricetin
Autoxidation
Covalent modification
Online Access:http://www.sciencedirect.com/science/article/pii/S2667137921000217

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http://www.sciencedirect.com/science/article/pii/S2667137921000217

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