TranSNPs: A class of functional SNPs affecting mRNA translation potential revealed by fraction-based allelic imbalance

TranSNPs: A class of functional SNPs affecting mRNA translation potential revealed by fraction-based allelic imbalance

Summary: Few studies have explored the association between SNPs and alterations in mRNA translation potential. We developed an approach to identify SNPs that can mark allele-specific protein expression levels and could represent sources of inter-individual variation in disease risk. Using MCF7 cells...

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Bibliographic Details
Main Authors: Samuel Valentini, Caterina Marchioretti, Alessandra Bisio, Annalisa Rossi, Sara Zaccara, Alessandro Romanel, Alberto Inga
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:iScience
Subjects:
Molecular mechanism of gene regulation
Computational bioinformatics
Transcriptomics
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221015029

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http://www.sciencedirect.com/science/article/pii/S2589004221015029

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