Inhibitors of cyclooxygenase-2-dependent modulation of functional characteristics of leukocytes
Cyclooxygenase (COX), the primary enzyme responsible for the synthesis of prostanoids, exists in at least 2 isoforms. COX-2 has been suggested to be the isoform primarily responsible for synthesis of prostaglandins (PGs) in the context of inflammation. Thus, selective inhibitors of COX-2 were develo...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Peoples’ Friendship University of Russia (RUDN University)
2009-03-01
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| Series: | RUDN Journal of Medicine |
| Online Access: | http://journals.rudn.ru/medicine/article/view/3776 |