Breast Cancer Chemotherapeutic Options: A General Overview on the Preclinical Validation of a Multi-Target Ruthenium(III) Complex Lodged in Nucleolipid Nanosystems

Breast Cancer Chemotherapeutic Options: A General Overview on the Preclinical Validation of a Multi-Target Ruthenium(III) Complex Lodged in Nucleolipid Nanosystems

In this review we have showcased the preclinical development of original amphiphilic nanomaterials designed for ruthenium-based anticancer treatments, to be placed within the current metallodrugs approach leading over the past decade to advanced multitarget agents endowed with limited toxicity and r...

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Bibliographic Details
Main Authors: Maria Grazia Ferraro, Marialuisa Piccolo, Gabriella Misso, Francesco Maione, Daniela Montesarchio, Michele Caraglia, Luigi Paduano, Rita Santamaria, Carlo Irace
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Cells
Subjects:
breast cancer (BC) therapy
ruthenium complexes
ruthenium-based nanosystems
preclinical studies
cell death pathways
multitarget drugs
Online Access:https://www.mdpi.com/2073-4409/9/6/1412

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https://www.mdpi.com/2073-4409/9/6/1412

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