Lack of Response to Imatinib in Melanoma Carrying Rare KIT Mutation р.T632I

Approximately 15% of acral and mucous melanomas carry activating mutations in KIT oncogene. There is a diversity of spectrum of KIT mutations, with some of them rendering tumors responsive to imatinib, while others being imatinib-resistant or not studied yet. Here we present an acral melanoma patien...

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Bibliographic Details
Main Authors: Kristina V. Orlova, Grigory A. Yanus, Svetlana N. Aleksakhina, Aigul R. Venina, Aglaya G. Iyevleva, Lev V. Demidov, Evgeny N. Imyanitov
Format: Article
Language:English
Published: Karger Publishers 2019-01-01
Series:Case Reports in Oncology
Subjects:
Online Access:https://www.karger.com/Article/FullText/495782