MicroRNA-378 contributes to osteoarthritis by regulating chondrocyte autophagy and bone marrow mesenchymal stem cell chondrogenesis

MicroRNA-378 contributes to osteoarthritis by regulating chondrocyte autophagy and bone marrow mesenchymal stem cell chondrogenesis

Osteoarthritis (OA) is the most common joint disease; thus, understanding the pathological mechanisms of OA initiation and progression is critical for OA treatment. MicroRNAs (miRNAs) have been shown to be involved in the progression of osteoarthritis, one candidate is microRNA-378 (miR-378), which...

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Bibliographic Details
Main Authors: Lu Feng, Zhengmeng Yang, Yucong Li, Qi Pan, Xiaoting Zhang, Xiaomin Wu, Jessica Hiu Tung Lo, Haixing Wang, Shanshan Bai, Xuan Lu, Ming Wang, Sien Lin, Xiaohua Pan, Gang Li
Format: Article
Language:English
Published: Elsevier 2022-06-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
miR-378
osteoarthritis
chondrocytes
autophagy
mesenchymal stem cells
chondrogenesis
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253122000658

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http://www.sciencedirect.com/science/article/pii/S2162253122000658

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