Direct imaging of hippocampal epileptiform calcium motifs following kainic acid administration in freely behaving mice
Prolonged exposure to abnormally high calcium concentrations is thought to be a core mechanism underlying hippocampal damage in epileptic patients; however, no prior study has characterized calcium activity during seizures in the live, intact hippocampus. We have directly investigated this possibili...
Main Authors: | Tamara K Berdyyeva, E. Paxon eFrady, Jonathan J Nassi, Leah eAluisio, Yauheniya eCherkas, Stephani eOtte, Ryan M Wyatt, Christine eDugovic, Kunal K Ghosh, Mark J Schnitzer, Timothy eLovenberg, Pascal eBonaventure |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2016-02-01
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Series: | Frontiers in Neuroscience |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fnins.2016.00053/full |
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