Improved therapeutic consistency and efficacy of CD317+ MSCs through stabilizing TSG6 by PTX3

Improved therapeutic consistency and efficacy of CD317+ MSCs through stabilizing TSG6 by PTX3

Abstract Background Previously, we have demonstrated that the batch variations of human platelet lysate (conventional MSC expansion medium) induce MSC heterogeneity and therapeutic inconsistency. On the other hand, the MSCs expanded with chemical defined medium have improved therapeutic consistency....

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Bibliographic Details
Main Authors: Shaoquan Shi, Si Chen, Bowei Liang, Yumeng Li, Qi Ma, Meiqi Li, Jingting Zhang, Lan Yao, Jianyong Xu
Format: Article
Language:English
Published: BMC 2024-03-01
Series:Stem Cell Research & Therapy
Subjects:
Mesenchymal stem/stromal cells
MSCs
CD317
Therapeutic consistency
Therapeutic efficacy
Online Access:https://doi.org/10.1186/s13287-024-03706-3

Internet

https://doi.org/10.1186/s13287-024-03706-3

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