Characterization of transcriptome diversity and in vitro behavior of primary human high-risk breast cells

Abstract Biology and transcriptomes of non-cancerous human mammary epithelial cells at risk for breast cancer development were explored following primary isolation utilizing conditional reprogramming cell technology from mastectomy tissue ipsilateral to invasive breast cancer. Cultures demonstrated...

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Bibliographic Details
Main Authors: Sahar J. Alothman, Keunsoo Kang, Xuefeng Liu, Ewa Krawczyk, Redha I. Azhar, Rong Hu, David Goerlitz, Bhaskar V. Kallakury, Priscilla A. Furth
Format: Article
Language:English
Published: Nature Portfolio 2022-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-10246-4