Efficacy and safety of immune checkpoint inhibitors with or without radiotherapy in metastatic non-small cell lung cancer: A systematic review and meta-analysis

Efficacy and safety of immune checkpoint inhibitors with or without radiotherapy in metastatic non-small cell lung cancer: A systematic review and meta-analysis

Background and purpose: Although immune checkpoint inhibitors (ICIs) have become the first-line treatment for metastatic non-small cell lung cancer (mNSCLC), their efficacy is limited. Meanwhile, recent reports suggest that radiotherapy (RT) can activate the systemic antitumor immune response by inc...

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Bibliographic Details
Main Authors: Zijing Liu, Tiankai Xu, Pengyu Chang, Weijia Fu, Jiaying Wei, Chengcheng Xia, Qiang Wang, Man Li, Xiaoyu Pu, Fuxue Huang, Chao Ge, Yan Gao, Shouliang Gong, Chengjiang Liu, Lihua Dong
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Pharmacology
Subjects:
radiotherapy
immune checkpoint inhibitors
non-small cell lung cancer
safety
efficacy
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1064227/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2023.1064227/full

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