Lactate mediated metabolic crosstalk between cancer and immune cells and its therapeutic implications

Metabolism is central to energy generation and cell signaling in all life forms. Cancer cells rely heavily on glucose metabolism wherein glucose is primarily converted to lactate even in adequate oxygen conditions, a process famously known as “the Warburg effect.” In addition to cancer cells, Warbur...

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Bibliographic Details
Main Authors: Seyedeh Sahar Mortazavi Farsani, Vivek Verma
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1175532/full