A one-two punch targeting reactive oxygen species and fibril for rescuing Alzheimer’s disease

A one-two punch targeting reactive oxygen species and fibril for rescuing Alzheimer’s disease

Abstract Toxic amyloid-beta (Aβ) plaque and harmful inflammation are two leading symptoms of Alzheimer’s disease (AD). However, precise AD therapy is unrealizable due to the lack of dual-targeting therapy function, poor BBB penetration, and low imaging sensitivity. Here, we design a near-infrared-II...

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Bibliographic Details
Main Authors: Jiefei Wang, Ping Shangguan, Xiaoyu Chen, Yong Zhong, Ming Lin, Mu He, Yisheng Liu, Yuan Zhou, Xiaobin Pang, Lulu Han, Mengya Lu, Xiao Wang, Yang Liu, Huiqing Yang, Jingyun Chen, Chenhui Song, Jing Zhang, Xin Wang, Bingyang Shi, Ben Zhong Tang
Format: Article
Language:English
Published: Nature Portfolio 2024-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-44737-x

Internet

https://doi.org/10.1038/s41467-024-44737-x

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