Tumor Induced Inactivation of Natural Killer Cell Cytotoxic Function; Implication in Growth, Expansion and Differentiation of Cancer Stem Cells

<p>Accumulated evidence indicates that cytotoxic function of immune effectors is largely suppressed in the tumor microenvironment by a number of distinct effectors and their secreted factors. The aims of this review are to provide a rationale and a potential mechanism for immunosuppression in...

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Bibliographic Details
Main Author: Anahid Jewett, Han-Ching Tseng
Format: Article
Language:English
Published: Ivyspring International Publisher 2011-01-01
Series:Journal of Cancer
Online Access:http://www.jcancer.org/v02p0443.htm