Tumor Induced Inactivation of Natural Killer Cell Cytotoxic Function; Implication in Growth, Expansion and Differentiation of Cancer Stem Cells
<p>Accumulated evidence indicates that cytotoxic function of immune effectors is largely suppressed in the tumor microenvironment by a number of distinct effectors and their secreted factors. The aims of this review are to provide a rationale and a potential mechanism for immunosuppression in...
Main Author: | |
---|---|
Format: | Article |
Language: | English |
Published: |
Ivyspring International Publisher
2011-01-01
|
Series: | Journal of Cancer |
Online Access: | http://www.jcancer.org/v02p0443.htm |