2028 Discovery and evaluation of FOXP3 dimerization inhibitors

OBJECTIVES/SPECIFIC AIMS: Immuno-oncology (IO) strategies are promising new approaches for the treatment of a variety of malignancies, including multiple myeloma (MM). Regulatory T cells (Tregs), which suppress effector T cell function, are a limitation to durable IO responses. The transcription fac...

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Bibliographic Details
Main Authors: Ravyn Thompson, Cara Coleman, Nathan G. Dolloff
Format: Article
Language:English
Published: Cambridge University Press 2018-06-01
Series:Journal of Clinical and Translational Science
Online Access:https://www.cambridge.org/core/product/identifier/S2059866118000651/type/journal_article