A Perfusion Culture System for Assessing Bone Marrow Stromal Cell Differentiation on PLGA Scaffolds for Bone Repair

A Perfusion Culture System for Assessing Bone Marrow Stromal Cell Differentiation on PLGA Scaffolds for Bone Repair

Biomaterials development for bone repair is currently hindered by the lack of physiologically relevant in vitro testing systems. Here we describe the novel use of a bi-directional perfusion bioreactor to support the long term culture of human bone marrow stromal cells (BMSCs) differentiated on polyl...

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Bibliographic Details
Main Authors: Caroline Moser, Katie Bardsley, Alicia J. El Haj, Mauro Alini, Martin J. Stoddart, Jennifer J. Bara
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
perfusion bioreactor
MSCs
PLGA
bone repair
tissue engineering
Online Access:https://www.frontiersin.org/article/10.3389/fbioe.2018.00161/full

Internet

https://www.frontiersin.org/article/10.3389/fbioe.2018.00161/full

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