Alpha synuclein modulates mitochondrial Ca2+ uptake from ER during cell stimulation and under stress conditions
Abstract Alpha synuclein (a-syn) is an intrinsically disordered protein prevalent in neurons, and aggregated forms are associated with synucleinopathies including Parkinson’s disease (PD). Despite the biomedical importance and extensive studies, the physiological role of a-syn and its participation...
Main Authors: | Meraj Ramezani, Alice Wagenknecht-Wiesner, Tong Wang, David A. Holowka, David Eliezer, Barbara A. Baird |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-09-01
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Series: | npj Parkinson's Disease |
Online Access: | https://doi.org/10.1038/s41531-023-00578-x |
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