Hydroxypropyl Methylcellulose Bioadhesive Hydrogels for Topical Application and Sustained Drug Release: The Effect of Polyvinylpyrrolidone on the Physicomechanical Properties of Hydrogel

Hydroxypropyl Methylcellulose Bioadhesive Hydrogels for Topical Application and Sustained Drug Release: The Effect of Polyvinylpyrrolidone on the Physicomechanical Properties of Hydrogel

Hydrogels are homogeneous three-dimensional polymeric networks capable of holding large amounts of water and are widely used in topical formulations. Herein, the physicomechanical, rheological, bioadhesive, and drug-release properties of hydrogels containing hydroxypropyl methylcellulose (HPMC) and...

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Bibliographic Details
Main Authors: Patrick Pan, Darren Svirskis, Geoffrey I. N. Waterhouse, Zimei Wu
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Pharmaceutics
Subjects:
hydrogels
factorial design
controlled release
topical delivery
texture analysis
rheology
Online Access:https://www.mdpi.com/1999-4923/15/9/2360

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https://www.mdpi.com/1999-4923/15/9/2360

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