In vivo evaluation of tumor uptake and bio-distribution of 99mTc-labeled 1-thio-β-D-glucose and 5-thio-D-glucose in mice model

In vivo evaluation of tumor uptake and bio-distribution of 99mTc-labeled 1-thio-β-D-glucose and 5-thio-D-glucose in mice model

Abstract Background To investigate the capacity of 99mTc-labeled 1-thio-β-D-glucose (1-TG) and 5-thio-D-glucose (5-TG) to act as a marker for glucose consumption in tumor cells in vivo as well as to evaluate the biodistribution of 1-TG and 5-TG. We investigated the biodistribution, including tumor u...

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Bibliographic Details
Main Authors: Fabian Muehlberg, Konrad Mohnike, Oliver S. Grosser, Maciej Pech, Juergen Goldschmidt, Karl-Heinz Smalla, Ricarda Seidensticker, Muzaffer Reha Ümütlü, Sinan Deniz, Jens Ricke, Ingo G. Steffen, Osman Öcal, Max Seidensticker
Format: Article
Language:English
Published: SpringerOpen 2024-03-01
Series:EJNMMI Radiopharmacy and Chemistry
Subjects:
Technetium-99 m
Glucose
Carbohydrate
Tumor
SPECT
1-thio-β-D-glucose
Online Access:https://doi.org/10.1186/s41181-024-00253-3

Internet

https://doi.org/10.1186/s41181-024-00253-3

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