Characteristics of mismatched eplets affecting de novo donor-specific antibody production and antibody-mediated rejection after kidney transplantation

Abstract De novo donor-specific antibody (dnDSA) generation is the most important marker of antibody-mediated rejection (AMR). However, not all dnDSAs induce AMR. The effects of mismatched eplets on dnDSA production and the occurrence AMR remain controversial. We analyzed 64 cases of dnDSA positive...

Full description

Bibliographic Details
Main Authors: Mei-He Li, Gu-Xiang Zhou, Ping Lan, Yi-Xuan Li, Xuan Zhang, Pei-Dan Kuang, Ying Zhang, Ying Wang, Min-Yue Zhang, Xiao-Ming Ding, Wu-Jun Xue, Jin Zheng
Format: Article
Language:English
Published: BMC 2025-02-01
Series:BMC Nephrology
Subjects:
Online Access:https://doi.org/10.1186/s12882-025-04016-3