Differential Elevation of Inflammation and CD4+ T Cell Activation in Kenyan Female Sex Workers and Non-Sex Workers Using Depot-Medroxyprogesterone Acetate

Differential Elevation of Inflammation and CD4+ T Cell Activation in Kenyan Female Sex Workers and Non-Sex Workers Using Depot-Medroxyprogesterone Acetate

BackgroundDepot Medroxyprogesterone (DMPA) is one of the most widely used contraceptives in Sub-Saharan Africa where HIV incidence is high. We explored the effect of DMPA on the activation of HIV cellular targets and inflammation as a possible mechanism of increased HIV risk with DMPA use. Since sex...

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Bibliografiska uppgifter
Huvudupphovsmän: Kenneth Omollo, Julie Lajoie, Julius Oyugi, Jocelyn M. Wessels, Dufton Mwaengo, Joshua Kimani, Charu Kaushic, Keith R. Fowke
Materialtyp: Artikel
Språk:English
Publicerad: Frontiers Media S.A. 2021-02-01
Serie:Frontiers in Immunology
Ämnen:
DMPA
inflammation
T-cell activation
HIV target cells
endocervix
commercial sex workers
Länkar:https://www.frontiersin.org/articles/10.3389/fimmu.2020.598307/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2020.598307/full

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