Hype or hope? High placebo response in major depression treatment with ketamine and esketamine: a systematic review and meta-analysis

BackgroundKetamine and esketamine offer a novel approach in the pharmacological treatment of major depressive disorder (MDD). This meta-analysis aimed to investigate the placebo response in double-blind, randomized controlled studies (RCTs) on patients with MDD receiving ketamine or esketamine.Metho...

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Bibliographic Details
Main Authors: Alexandros Matsingos, Marcel Wilhelm, Laila Noor, Cüneyt Yildiz, Winfried Rief, Stefan G. Hofmann, Irina Falkenberg, Tilo Kircher
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Psychiatry
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2024.1346697/full