HR-MS Based Untargeted Lipidomics Reveals Characteristic Lipid Signatures of Wilson’s Disease

HR-MS Based Untargeted Lipidomics Reveals Characteristic Lipid Signatures of Wilson’s Disease

Background and Aims: The diagnosis of Wilson’s disease (WD) is challenging by clinical or genetic criteria. A typical early pathological change of WD is the increased liver lipid deposition and lowered serum triglyceride (TG). Therefore, the contents of serum lipids may provide evidence for screenin...

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Bibliographic Details
Main Authors: Yixiao Zhi, Yujiao Sun, Yonggeng Jiao, Chen Pan, Zeming Wu, Chang Liu, Jie Su, Jie Zhou, Dong Shang, Junqi Niu, Rui Hua, Peiyuan Yin
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Pharmacology
Subjects:
Wilson disease
lipidomics
biomarkers
triglyceride
metabolomic
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.754185/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.754185/full

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