Upregulation of the coagulation factor VII gene during glucose deprivation is mediated by activating transcription factor 4.

Upregulation of the coagulation factor VII gene during glucose deprivation is mediated by activating transcription factor 4.

BACKGROUND: Constitutive production of blood coagulation proteins by hepatocytes is necessary for hemostasis. Stressful conditions trigger adaptive cellular responses and delay processing of most proteins, potentially affecting plasma levels of proteins secreted exclusively by hepatocytes. We examin...

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Bibliographic Details
Main Authors: Katherine R Cronin, Thomas P Mangan, Josephine A Carew
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3407153?pdf=render

Internet

http://europepmc.org/articles/PMC3407153?pdf=render

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