TSPAN4-positive migrasome derived from retinal pigmented epithelium cells contributes to the development of proliferative vitreoretinopathy

TSPAN4-positive migrasome derived from retinal pigmented epithelium cells contributes to the development of proliferative vitreoretinopathy

Abstract Background Proliferative vitreoretinopathy (PVR) is a blind-causing disease initiated by the activation of retinal pigmented epithelium (RPE) primarily induced by TGF-β families. Migrasome is a recently discovered type of extracellular vesicle related to cell migration. Results Here, we use...

Full description

Bibliographic Details
Main Authors: Liangjing Wu, Shuai Yang, Hui Li, Yao Zhang, Le Feng, Conghui Zhang, Jiayi Wei, Xunyi Gu, Guotong Xu, Zhaoyang Wang, Fang Wang
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Journal of Nanobiotechnology
Subjects:
Migrasome
tetraspanin4
Epithelial–mesenchymal transition
Retinal pigmented epithelium
Proliferative vitreoretinopathy
Online Access:https://doi.org/10.1186/s12951-022-01732-y

Internet

https://doi.org/10.1186/s12951-022-01732-y

Similar Items