Xc- System as a Possible Target for ConBr Lectin Interaction in Glioma Cells

Xc- System as a Possible Target for ConBr Lectin Interaction in Glioma Cells

Studies have revealed the dependence of glioma cells on iron, making them sensitive to ferroptosis. Ferroptosis can be triggered by inhibition of the xc- system, resulting in redox imbalance and membrane lipid peroxidation. The xc- system is composed of two coupled proteins, xCT and CD98hc. The cont...

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Bibliographic Details
Main Authors: Vanir Reis Pinto-Junior, Rodrigo Lopes Seeger, Cláudio Henrique Dahne Souza-Filho, Angela Patricia França, Nicole Sartori, Messias Vital Oliveira, Vinicius Jose Silva Osterne, Kyria Santiago Nascimento, Rodrigo Bainy Leal, Benildo Sousa Cavada
Format: Article
Language:English
Published: MDPI AG 2024-07-01
Series:Neuroglia
Subjects:
glioma
lectin
xc- system
Online Access:https://www.mdpi.com/2571-6980/5/3/15

Internet

https://www.mdpi.com/2571-6980/5/3/15

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