Single-shot, coherent, pop-out 3D metrology

Abstract Three-dimensional (3D) imaging of thin, extended specimens at nanometer resolution is critical for applications in biology, materials science, advanced synthesis, and manufacturing. One route to 3D imaging is tomography, which requires a tilt series of a local region. However, capturing ima...

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Main Authors: Deepan Balakrishnan, See Wee Chee, Zhaslan Baraissov, Michel Bosman, Utkur Mirsaidov, N. Duane Loh
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Communications Physics
Online Access:https://doi.org/10.1038/s42005-023-01431-6
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author Deepan Balakrishnan
See Wee Chee
Zhaslan Baraissov
Michel Bosman
Utkur Mirsaidov
N. Duane Loh
author_facet Deepan Balakrishnan
See Wee Chee
Zhaslan Baraissov
Michel Bosman
Utkur Mirsaidov
N. Duane Loh
author_sort Deepan Balakrishnan
collection DOAJ
description Abstract Three-dimensional (3D) imaging of thin, extended specimens at nanometer resolution is critical for applications in biology, materials science, advanced synthesis, and manufacturing. One route to 3D imaging is tomography, which requires a tilt series of a local region. However, capturing images at higher tilt angles is infeasible for such thin, extended specimens. Here, we explore a suitable alternative to reconstruct the 3D volume using a single, energy-filtered, bright-field coherent image. We show that when our specimen is homogeneous and amorphous, simultaneously inferring local depth and thickness for 3D imaging is possible in the near-field limit. We demonstrated this technique with a transmission electron microscope to fill a glaring gap for rapid, accessible 3D nanometrology. This technique is applicable, in general, to any coherent bright field imaging with electrons, photons, or any other wavelike particles.
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spelling doaj.art-cdad1fa7f5954e2597ada6725a1690562023-11-05T12:20:40ZengNature PortfolioCommunications Physics2399-36502023-11-016111510.1038/s42005-023-01431-6Single-shot, coherent, pop-out 3D metrologyDeepan Balakrishnan0See Wee Chee1Zhaslan Baraissov2Michel Bosman3Utkur Mirsaidov4N. Duane Loh5Centre for Bio-Imaging Sciences, National University of SingaporeCentre for Bio-Imaging Sciences, National University of SingaporeCentre for Bio-Imaging Sciences, National University of SingaporeDepartment of Materials Science and Engineering, National University of SingaporeCentre for Bio-Imaging Sciences, National University of SingaporeCentre for Bio-Imaging Sciences, National University of SingaporeAbstract Three-dimensional (3D) imaging of thin, extended specimens at nanometer resolution is critical for applications in biology, materials science, advanced synthesis, and manufacturing. One route to 3D imaging is tomography, which requires a tilt series of a local region. However, capturing images at higher tilt angles is infeasible for such thin, extended specimens. Here, we explore a suitable alternative to reconstruct the 3D volume using a single, energy-filtered, bright-field coherent image. We show that when our specimen is homogeneous and amorphous, simultaneously inferring local depth and thickness for 3D imaging is possible in the near-field limit. We demonstrated this technique with a transmission electron microscope to fill a glaring gap for rapid, accessible 3D nanometrology. This technique is applicable, in general, to any coherent bright field imaging with electrons, photons, or any other wavelike particles.https://doi.org/10.1038/s42005-023-01431-6
spellingShingle Deepan Balakrishnan
See Wee Chee
Zhaslan Baraissov
Michel Bosman
Utkur Mirsaidov
N. Duane Loh
Single-shot, coherent, pop-out 3D metrology
Communications Physics
title Single-shot, coherent, pop-out 3D metrology
title_full Single-shot, coherent, pop-out 3D metrology
title_fullStr Single-shot, coherent, pop-out 3D metrology
title_full_unstemmed Single-shot, coherent, pop-out 3D metrology
title_short Single-shot, coherent, pop-out 3D metrology
title_sort single shot coherent pop out 3d metrology
url https://doi.org/10.1038/s42005-023-01431-6
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AT zhaslanbaraissov singleshotcoherentpopout3dmetrology
AT michelbosman singleshotcoherentpopout3dmetrology
AT utkurmirsaidov singleshotcoherentpopout3dmetrology
AT nduaneloh singleshotcoherentpopout3dmetrology