Immunopathology of and potential therapeutics for secondary hemophagocytic lymphohistiocytosis/macrophage activation syndrome: a translational perspective

Abstract Secondary hemophagocytic lymphohistiocytosis/macrophage activation syndrome (sHLH/MAS) is a life-threatening immune disorder triggered by rheumatic disease, infections, malignancies, or medications. Characterized by the presence of hemophagocytic macrophages and a fulminant cytokine storm,...

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Bibliographic Details
Main Authors: Tram T. T. Nguyen, Yoon Tae Kim, Geunyeol Jeong, Mirim Jin
Format: Article
Language:English
Published: Nature Publishing Group 2024-03-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-024-01182-6