PR3-ANCAs Detected by Third-Generation ELISA Predicts Severe Disease and Poor Survival in Primary Sclerosing Cholangitis

PR3-ANCAs Detected by Third-Generation ELISA Predicts Severe Disease and Poor Survival in Primary Sclerosing Cholangitis

A highly sensitive detection of anti-neutrophil cytoplasmic antibodies to serine proteinase-3 (PR3-ANCAs) aids in the serological diagnosis of autoimmune liver disorders and the prediction of severity in primary sclerosing cholangitis (PSC). Here, we evaluate a novel third-generation ELISA for the d...

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Detalhes bibliográficos
Principais autores: Steffi Lopens, Ewa Wunsch, Malgorzata Milkiewicz, Nadja Röber, Grit Zarske, Abdullah Nasser, Karsten Conrad, Martin Laass, Stefan Rödiger, Marcin Krawczyk, Dirk Roggenbuck, Piotr Milkiewicz
Formato: Artigo
Idioma:English
Publicado em: MDPI AG 2022-11-01
coleção:Diagnostics
Assuntos:
primary sclerosing cholangitis
antibodies against serine protease proteinase-3
survival
health-related quality of life
liver biochemistry
disease severity
Acesso em linha:https://www.mdpi.com/2075-4418/12/11/2682

Internet

https://www.mdpi.com/2075-4418/12/11/2682

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