Simultaneous Analysis of Wnt and NF-κB Signaling Pathways in Doxorubicin Sensitive and Methotrexate Resistant PLC/ PRF/5 Cells

Objective: Multi-drug resistance (MDR) is a controversial issue in traditional chemotherapy of aggressive cancers, including hepatocellular carcinoma. The major cause of MDR is suggested to be the aberrant activation of the main signaling pathways such as Wnt and nuclear factor kappa-light-chain-...

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Bibliographic Details
Main Authors: Nasrin Shojaie, Seyed Mahmood Ghaffari
Format: Article
Language:English
Published: Royan Institute (ACECR), Tehran 2016-02-01
Series:Cell Journal
Subjects:
Online Access:http://celljournal.org/web/journal/article/1230/download