Effect of G-quadruplex polymorphism on the recognition of telomeric DNA by a metal complex.

The physiological role(s) played by G-quadruplexes renders these 'non-canonical' DNA secondary structures interesting new targets for therapeutic intervention. In particular, the search for ligands for selective recognition and stabilization of G-quadruplex arrangements has led to a number...

Full description

Bibliographic Details
Main Authors: Caterina Musetti, A Paul Krapcho, Manlio Palumbo, Claudia Sissi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3596309?pdf=render