A flexible framework for multi-particle refinement in cryo-electron tomography.

Cryo-electron tomography (cryo-ET) and subtomogram averaging (STA) are increasingly used for macromolecular structure determination in situ. Here, we introduce a set of computational tools and resources designed to enable flexible approaches to STA through increased automation and simplified metadat...

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Bibliographic Details
Main Authors: Alister Burt, Lorenzo Gaifas, Tom Dendooven, Irina Gutsche
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-08-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3001319