Single-cell transcriptome analysis reveals the immune heterogeneity and the repopulation of microglia by Hif1α in mice after spinal cord injury

Single-cell transcriptome analysis reveals the immune heterogeneity and the repopulation of microglia by Hif1α in mice after spinal cord injury

Abstract Neuroinflammation is regarded as a vital pathological process in spinal cord injury (SCI), which removes damaged tissue, secretes cytokines, and facilitates regeneration. Repopulation of microglia has been shown to favor recovery from SCI. However, the origin and regulatory factors of micro...

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Bibliographic Details
Main Authors: Jingyu Wang, Lintao Xu, Weiwei Lin, Yin Yao, Heyangzi Li, Gerong Shen, Xi Cao, Ning He, Jun Chen, Jue Hu, Mingzhi Zheng, Xinghui Song, Yuemin Ding, Yueliang Shen, Jinjie Zhong, Lin-lin Wang, Ying-ying Chen, Yongjian Zhu
Format: Article
Language:English
Published: Nature Publishing Group 2022-05-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-022-04864-z

Internet

https://doi.org/10.1038/s41419-022-04864-z

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