Tandem RNA chimeras contribute to transcriptome diversity in human population and are associated with intronic genetic variants.

Chimeric RNAs originating from two or more different genes are known to exist not only in cancer, but also in normal tissues, where they can play a role in human evolution. However, the exact mechanism of their formation is unknown. Here, we use RNA sequencing data from 462 healthy individuals repre...

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Bibliographic Details
Main Authors: Liliana Greger, Jing Su, Johan Rung, Pedro G Ferreira, Geuvadis consortium, Tuuli Lappalainen, Emmanouil T Dermitzakis, Alvis Brazma
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4136775?pdf=render