Spatially coherent diffusion of human RNA Pol II depends on transcriptional state rather than chromatin motion

Gene transcription by RNA polymerase II (RNAPol II) is a tightly regulated process in the genomic, temporal, and spatial context. Recently, we have shown that chromatin exhibits spatially coherently moving regions over the entire nucleus, which is enhanced by transcription. Yet, it remains unclear h...

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Bibliographic Details
Main Authors: Roman Barth, Haitham A. Shaban
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:Nucleus
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/19491034.2022.2088988