Androgen and Estrogen β Receptor Expression Enhances Efficacy of Antihormonal Treatments in Triple-Negative Breast Cancer Cell Lines

Androgen and Estrogen β Receptor Expression Enhances Efficacy of Antihormonal Treatments in Triple-Negative Breast Cancer Cell Lines

The triple-negative breast cancer (TNBC) subtype is characterized by the lack of expression of ERα (estrogen receptor α), PR (progesterone receptor) and no overexpression of HER-2. However, TNBC can express the androgen receptor (AR) or estrogen receptor β (ERβ). Also, TNBC secretes steroid hormones...

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Bibliographic Details
Main Authors: Belen Crespo, Juan Carlos Illera, Gema Silvan, Paula Lopez-Plaza, María Herrera de la Muela, Miriam de la Puente Yagüe, Cristina Diaz del Arco, Maria Jose Illera, Sara Caceres
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:International Journal of Molecular Sciences
Subjects:
androgen receptor
estrogen receptor beta
steroid pathway
triple-negative breast cancer
Online Access:https://www.mdpi.com/1422-0067/25/3/1471

Internet

https://www.mdpi.com/1422-0067/25/3/1471

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