NT1-Tau Is Increased in CSF and Plasma of CJD Patients, and Correlates with Disease Progression

NT1-Tau Is Increased in CSF and Plasma of CJD Patients, and Correlates with Disease Progression

This study investigates the diagnostic and prognostic potential of different forms of tau in biofluids from patients with Creutzfeldt-Jakob disease (CJD). Extracellular tau, which is molecularly heterogeneous, was measured using ultra-sensitive custom-made Simoa assays for N-terminal (NT1), mid-regi...

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Bibliographic Details
Main Authors: David Mengel, Tze How Mok, Akin Nihat, Wen Liu, Robert A. Rissman, Douglas Galasko, Henrik Zetterberg, Simon Mead, John Collinge, Dominic M. Walsh
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Cells
Subjects:
Alzheimer’s disease
biomarker
blood
cerebrospinal fluid
neurodegeneration
neurofilament light chain
Online Access:https://www.mdpi.com/2073-4409/10/12/3514

Internet

https://www.mdpi.com/2073-4409/10/12/3514

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