The Effect of Liposomal Diallyl Disulfide and Oxaliplatin on Proliferation of Colorectal Cancer Cells: In Vitro and In Silico Analysis

The Effect of Liposomal Diallyl Disulfide and Oxaliplatin on Proliferation of Colorectal Cancer Cells: In Vitro and In Silico Analysis

Diallyl disulfide (DADS) is one of the main bioactive organosulfur compounds of garlic, and its potential against various cancer models has been demonstrated. The poor solubility of DADS in aqueous solutions limits its uses in clinical application. The present study aimed to develop a novel formulat...

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Bibliographic Details
Main Authors: Faris Alrumaihi, Masood Alam Khan, Ali Yousif Babiker, Mohammed Alsaweed, Faizul Azam, Khaled S. Allemailem, Ahmad A. Almatroudi, Syed Rizwan Ahamad, Naif AlSuhaymi, Mahdi H. Alsugoor, Ahmed N. Algefary, Arif Khan
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Pharmaceutics
Subjects:
diallyl disulfide liposomes
oxaliplatin stealth liposomes
synergism
colorectal cancer
in silico modeling
Online Access:https://www.mdpi.com/1999-4923/14/2/236

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https://www.mdpi.com/1999-4923/14/2/236

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