The Effect of Rev-erbα Agonist SR9011 on the Immune Response and Cell Metabolism of Microglia

Microglia are the immune cells of the brain. Hyperactivation of microglia contributes to the pathology of metabolic and neuroinflammatory diseases. Evidence has emerged that links the circadian clock, cellular metabolism, and immune activity in microglia. Rev-erb nuclear receptors are known for thei...

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Bibliographic Details
Main Authors: Samantha E. C. Wolff, Xiao-Lan Wang, Han Jiao, Jia Sun, Andries Kalsbeek, Chun-Xia Yi, Yuanqing Gao
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.550145/full