Roles of Post-translational Modifications in Spinocerebellar Ataxias

Roles of Post-translational Modifications in Spinocerebellar Ataxias

Post-translational modifications (PTMs), including phosphorylation, acetylation, ubiquitination, SUMOylation, etc., of proteins can modulate protein properties such as intracellular distribution, activity, stability, aggregation, and interactions. Therefore, PTMs are vital regulatory mechanisms for...

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Bibliographic Details
Main Authors: Linlin Wan, Keqin Xu, Zhao Chen, Beisha Tang, Hong Jiang
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Cellular Neuroscience
Subjects:
post-translational modification
spinocerebellar ataxias
protein
pathogenesis
therapy
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2018.00290/full

Internet

https://www.frontiersin.org/article/10.3389/fncel.2018.00290/full

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