Engineered Lysins With Customized Lytic Activities Against Enterococci and Staphylococci

Engineered Lysins With Customized Lytic Activities Against Enterococci and Staphylococci

The emergence of multidrug-resistant bacteria has made minor bacterial infections incurable with many existing antibiotics. Lysins are phage-encoded peptidoglycan hydrolases that have demonstrated therapeutic potential as a novel class of antimicrobials. The modular architecture of lysins enables th...

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Bibliographic Details
Main Authors: Hana Sakina Binte Muhammad Jai, Linh Chi Dam, Lowella Servito Tay, Jodi Jia Wei Koh, Hooi Linn Loo, Kimberly A. Kline, Boon Chong Goh
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Microbiology
Subjects:
lysin
Enterococcus
Staphylococcus
endolysin
antibiotic alternatives
antimicrobial resistance
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2020.574739/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2020.574739/full

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